This is a dynamic course in plant-human interaction that bridges cultural anthropology and related disciplines like economic botany, archaeology, and environmental history to explore a selection of economic plants that have shaped human society. This course follows case studies of select taxa to explore their origins and past uses, impacts of colonial encounters, effects of climate change, and other contemporary social and political entanglements. Special attention will be given to issues of plant use and Indigenous resilience, sovereignty, and cultural revitalization, as well as potential contributions to sustainable futures and agrobiodiversity.