This upper level course examines the structure and function of ion channels at the molecular level, including the biophysics of ion permeability, voltage-sensing, and activation by neurotransmitters. Approximately half of the course is student-led discussions on research papers that detail ion channel dysfunction that lead to disease. Prerequisite: (NEUR 208 or NEUR 225 or NEUR 254) and (BIOL 243 or BIOL 233 or PSYC 251).