Neuroscience

Website: Neuroscience

Multiple models of Neuroscience programs exist. While some focus on animal behavior, others operate in conjunction with the cognitive sciences or prioritize clinical behaviors. The Neuroscience program at Sewanee provides students with the depth of core Neuroscience knowledge, but also breadth of training outside of Neuroscience in the natural sciences, psychology, mathematics, and philosophy resulting in multidisciplinary discourse.

Professors: Bachman, Kikis, Miles, Pongdee, Yu, Zigler

Associate Professors: Bateman, Cammack (Chair), Seballos, Shelley, A. Summers

Assistant Professor: Reppert

Neuroscience is a highly interdisciplinary field that spans the study of everything from single molecules to brain-wide circuits. The Sewanee neuroscience curriculum is designed to provide a fundamental understanding of cellular /molecular, behavioral, and cognitive approaches to exploring the brain. Flexible electives allow our students to expand their training into many related fields, including biomedical and health sciences, computational modeling, chemistry, and philosophy. Our professors provide a welcoming and collaborative environment where our students develop critical thinking skills, creativity, and a rigorous approach to understanding neuroscientific research.

Requirements for the Major in Neuroscience

The major requires successful completion of the following:

Course Requirements 1
Three introductory courses:
NEUR 101Introduction to Neuroscience4
BIOL 133Introductory Molecular Biology and Genetics4
CHEM 119Principles of Chemistry4
or CHEM 120 General Chemistry (Lab)
or CHEM 150 Advanced General Chemistry (Lab)
Two intermediate courses:
NEUR 208Neurobiology4
NEUR 220Behavioral Cognitive Neuroscience4
Select one of the following statistics / methods courses:4
Experimental Design and Data Analysis in Biology (Lab)
Molecular Methods (Lab)
Research Methods and Data Analysis (Lab)
Select three of the following, including one laboratory course:12
Experimental Neurobiology (Lab)
Advanced Cognitive Neuroscience (Lab)
Advanced Behavioral Neuroscience (Lab)
Drugs and Behavior (Lab)
Ion Channels and Disease
Neuroscience of Preference and Choice
Drugs and Behavior
Addiction
Cognitive Science
Consciousness and Unconsciousness: Explorations in Neurophilosophy
Select a course from two of the following groups: 28
Select a course from two of the following groups:8
Genetics (Lab)
Genetics
Molecular Cell Biology
Biochemistry
Molecular Methods (Lab)
Human Anatomy (Lab)
General and Human Physiology
General and Human Physiology (Lab)
Genes and Behavior
Biology of Aging
Organic Chemistry I (Lab)
Group B (attribute NGPB)
Introduction to Modeling and Programming
General Physics I (Lab)
Modern Mechanics (Lab)
Data Science and Citizenship
Elementary Statistics
Group C (attribute NGPC)
Clinical Psychology
Cognitive Psychology
Adolescence
Adult Development and Aging
Group D (attribute NGPD)
Being Human in STEM
Informal Logic and Critical Thinking
The Self
Bioethics
Modern Logic
Total Semester Hours52
Additional Requirements
A comprehensive examination 3
1

Majors must complete at least three laboratory courses, labeled “(Lab)” above. Majors will complete two of these lab courses in the process of fulfilling specific major requirements (i.e., the Statistics/Methods course and a neuroscience lab course). The third lab course may be completed if the student takes CHEM 120 or CHEM 150; if the student chooses to take CHEM 119, they may take any other (Lab) course listed in the major requirements as their third laboratory course."

2

In developing the major, the Neuroscience Steering Committee has created cross-disciplinary and field-expanding opportunities and has included courses expected to offer a fruitful integration with Neuroscience. The elective lists include courses with subject matter that is implicitly related to the study of behavior or cognition, or tangential to Neuroscience as a discipline but with theoretical relevance. Such courses must be completed by students wishing to pursue graduate work in neuroscience (or biology or psychology) or students interested in the health professions, as they are typically required before admission to those programs.

3

Students participating in the Sewanee-at-Yale semester program should contact the neuroscience chair to discuss relevant course offerings.

4

The comprehensive examination allows the Neuroscience Steering Committee to assess students' understanding of basic neuroscience knowledge, and their ability to: identify important questions related to their field of interest, exhibit knowledge of experimental design, think critically about experimental methodology and analysis, and integrate and synthesize information from other courses and sub-disciplines.

A minor in neuroscience allows students to consider how brain-function relates to behavior, and to explore one of the most compelling scientific frontiers in understanding ourselves and our actions. The minor examines the nervous system and its contribution to our experiences through a truly interdisciplinary approach. Students are required to take courses in both psychology and biology, and are highly encouraged to explore related courses within chemistry, computer science, and philosophy.


The goal of the neuroscience minor is to encourage students to critically evaluate how the brain functions from the molecular and cellular level, and how these processes affect behavior. The neuroscience minor is ideal for students with an interest in any neuroscience-related field. The minor prepares students for graduate study in neuroscience or related fields, and is also a good preparation for those planning to pursue a career in medicine and related disciplines.

Requirements for the Minor in Neuroscience

The minor requires successful completion of the following:

Course Requirements 1
NEUR 101Introduction to Neuroscience4
Select four of the following:16
Biology of Aging
Neurobiology
Cognitive Neuroscience
Behavioral Neuroscience
Experimental Neurobiology (Lab)
Advanced Behavioral Neuroscience (Lab)
Ion Channels and Disease
Drugs and Behavior
Drugs and Behavior (Lab)
Cognitive Science
Addiction
Select one course from any of the following five groups: 2, 34
Select one course from any of the following five groups:4
Genetics (Lab)
Genetics
Molecular Cell Biology
Biochemistry
Molecular Methods (Lab)
Human Anatomy (Lab)
General and Human Physiology
General and Human Physiology (Lab)
Genes and Behavior
Biology of Aging
Organic Chemistry I (Lab)
Group B (attribute NGPB)
Introduction to Modeling and Programming
General Physics I (Lab)
Modern Mechanics (Lab)
Data Science and Citizenship
Elementary Statistics
Group C (attribute NGPC)
Clinical Psychology
Cognitive Psychology
Adolescence
Adult Development and Aging
Group D (attribute NGPD)
Being Human in STEM
Informal Logic and Critical Thinking
The Self
Bioethics
Modern Logic
Group E (attribute NGPE)
Experimental Neurobiology (Lab)
Advanced Cognitive Neuroscience (Lab)
Advanced Behavioral Neuroscience (Lab)
Ion Channels and Disease
Drugs and Behavior
Drugs and Behavior (Lab)
Addiction
Total Semester Hours28
1

In addition to the required statistics/methods and neuroscience laboratory courses, one additional laboratory science course is required. This course may be selected from the laboratory science courses designated above in Groups A-E or in the introductory Chemistry requirement.

2

Students participating in the Sewanee-at-Yale semester program should contact the Neuroscience Chair to discuss relevant course offerings.

NEUR 101     Introduction to Neuroscience  (4)

This course provides an introduction to the structure and function of the central and peripheral nervous systems. Fundamental concepts and topics in neuroscience will be discussed using molecular/cellular, behavioral and/or cognitive frameworks; clinically relevant conditions (e.g., neurodegenerative diseases, psychiatric disorders) will also be explored. Methods and techniques used by neuroscientists in research laboratories and clinical settings will be used to understand how neuroscience knowledge is constructed.

NEUR 195     Introduction to Research  (2 or 4)

An introduction to research methods and hypothesis-driven laboratory research in the context of a faculty member’s research program. Activities may include literature reviews, training in laboratory techniques, and/or analyzing data. This course may be repeated for credit at the discretion of the instructor. Prerequisite: Instructor prerequisite override required.

NEUR 208     Neurobiology  (4)

A comprehensive study of the biology of the nervous system covering its overall organization and development, electrical and chemical signaling, synaptic plasticity, and mechanisms of sensory perception and motor function. Non-laboratory course. Prerequisite: (CHEM 119 or CHEM 120 or CHEM 150) and (NEUR 101 or BIOL 133).

NEUR 220     Behavioral Cognitive Neuroscience  (4)

This course explores the neural mechanisms underlying behavior and cognition. Topics may include motivation, learning and memory, emotion, stress, sleep and circadian rhythms, attention, and decision-making. Neuroscience methodology and preclinical models of psychiatric and neurodegenerative disorders will be discussed. Prerequisite: NEUR 101.

NEUR 225     Cognitive Neuroscience  (4)

This course provides a systems-level approach to the study of the mammalian nervous system. Content focuses on various aspects of cognitive processing, such as perception, attention, memory, learning, emotion, executive control and decision making. Prerequisite: NEUR 101.

NEUR 254     Behavioral Neuroscience  (4)

This course introduces major topics and techniques used by behavioral neuroscientists to study the relationship between the brain and behavior. Content may explore motivated behaviors, stress, learning and memory, control of movement, sleep and circadian rhythms, and preclinical models of psychiatric and neurodegenerative disorders. Prerequisite: NEUR 101.

NEUR 295     Mentored Research  (2 or 4)

Intermediate-level laboratory research in the context of a faculty member’s research program. Activities may include designing and/or conducting experiments, analyzing data, and written/oral presentation of findings. This course may be repeated for credit at the discretion of the instructor. Prerequisite: NEUR 195 and instructor prerequisite override required.

NEUR 351     Experimental Neurobiology (Lab)  (4)

This lecture and laboratory course utilizes electrical recordings from a variety of invertebrates to build upon topics discussed in NEUR 208, illustrating the principles of nervous system communication in sensory and motor systems. The course will also include the roles of hypothesis testing, models, data analysis, and the scientific method in understanding how experimental data can lead to knowledge of nervous system function. Prerequisite: NEUR 208.

NEUR 355     Advanced Cognitive Neuroscience (Lab)  (4)

This laboratory course provides an experimental approach to the study of cognitive processing, building on topics introduced in NEUR 225. Laboratory exercises may cover processes such as perception, attention, memory, learning and decision making. The course includes a focus on scientific methodology, including hypothesis testing, study design, data collection and analysis, and communication of results. Prerequisite: NEUR 225.

NEUR 359     Advanced Behavioral Neuroscience (Lab)  (4)

This inquiry-based laboratory course explores the relationship between the brain and behavior. Class research projects will focus on select topics in behavioral neuroscience. Students will engage with the scientific process by designing and conducting experiments to test hypotheses, collecting and analyzing data, and communicating results. Prerequisite: PSYC 254.

NEUR 395     Advanced Research  (2 or 4)

Advanced laboratory research for students who have a strong background in neuroscience research. Students will work with a faculty research mentor to design and conduct experiments aimed to address a novel scientific question. This course may be repeated for credit at the discretion of the instructor. Prerequisite: NEUR 295 and instructor prerequisite override required.

NEUR 415     Ion Channels and Disease  (4)

This upper level course examines the structure and function of ion channels at the molecular level, including the biophysics of ion permeability, voltage-sensing, and activation by neurotransmitters. Approximately half of the course is student-led discussions on research papers that detail ion channel dysfunction that lead to disease. Prerequisite: (NEUR 208 or NEUR 225 or NEUR 254) and (BIOL 243 or BIOL 233 or PSYC 251).

NEUR 416     Neuroscience of Preference and Choice  (4)

This seminar course examines topics related to the neuroeconomics of choice. Topics may include cognitive effort, temporal discounting, overconfidence, risk sensitivity, anchoring, and prospect theory. A significant portion of the course consists of student-led discussion of readings examining these topics. Readings focus on scholarly works featuring psychological and neurobiological perspectives. Prerequisite: NEUR 225 or PSYC 208.

NEUR 444     Independent Study  (2 or 4)

Students will complete directed readings and writing on a topic in neuroscience. Must be approved by the program chair. This course may be repeated for credit when the topic differs. Prerequisite: Instructor prerequisite override required.

NEUR 495     Topics in Neuroscience  (2 or 4)

Selected topics in neuroscience. Content will vary from semester to semester. This course may be repeated for credit when the topic differs. This course is only available through the Sewanee-at-Yale Directed Research Program. Prerequisite: Only open to students admitted to the Sewanee-at-Yale program.

NEUR 499     Directed Research  (4 or 8)

Students conduct research under the direction of a faculty member on a topic of mutual interest. Typically culminates in a written research report. This course is only available through the Yale Directed Research Program. Prerequisite: Only open to students admitted to the Sewanee-at-Yale program.